Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.55 |
| ▸ | MMP3 | P08254 | 12/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268879 | 0.86 | MMP2 (0.65) | MMP2MMP3 | |
| Trifluoroacetic Acid SCHEMBL7762284 | 0.82 | MMP2 (0.60) | MMP2MMP3 | |
| SCHEMBL7758482 | 0.76 | MMP2 (0.62) | MMP2MMP3 | |
| SCHEMBL10419244 | 0.73 | CNR1 (0.50) | SPHK1 | |
| SCHEMBL7763695 | 0.71 | MMP2 (0.73) | MMP2MMP3 | |
| SCHEMBL7758573 | 0.70 | MMP2 (0.71) | MMP2MMP3 | |
| SCHEMBL6557873 | 0.70 | RARB (0.51) | MMP2 | |
| SCHEMBL7763206 | 0.70 | MME (0.41) | — | |
| SCHEMBL7761531 | 0.70 | MMP2 (0.72) | MMP2MMP3 | |
| SCHEMBL19534347 | 0.69 | MMP2 (0.49) | MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | claimed |
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | disclosed |