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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7762284

CC(C)(C)C(NC(=O)C(CCCCc1ccc(-c2ccccc2)cc1)C(=O)O)C(=O)Nc1ccncc1.O=C(O)C(F)(F)F

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 20/20 0.60
▸ MMP3 P08254 14/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6268879 0.95 MMP2 (0.65) MMP2MMP3
SCHEMBL7758522 0.82 MMP2 (0.55) MMP2MMP3
SCHEMBL6808248 0.78 MMP2 (0.61) MMP2MMP3
SCHEMBL6808246 0.78 MMP2 (0.61) MMP2MMP3
SCHEMBL7758509 0.77 MMP2 (0.71) MMP2MMP3
SCHEMBL7026877 0.70 MMP2 (0.49) MMP2MMP3
Trifluoroacetic Acid SCHEMBL7608042 0.70 MMP2 (0.54) MMP2MMP3
Trifluoroacetic Acid SCHEMBL7669601 0.70 MMP2 (0.54) MMP2MMP3
SCHEMBL8649902 0.69 MMP2 (0.50) MMP2MMP3
SCHEMBL7763695 0.69 MMP2 (0.73) MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1098662-A2 COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS WARNER-LAMBERT COMPANY (US) 2001-05-16 — — EP claimed
WO-2000004892-A2 COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS WARNER-LAMBERT COMPANY (US) 2000-02-03 — — WO claimed