Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562356 | 0.79 | POLB (0.37) | POLBCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL8080652 | 0.79 | POLB (0.37) | POLBCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL26764167 | 0.75 | ALDH1A1 (0.39) | POLBALOX15TSHR | |
| SCHEMBL23641866 | 0.71 | GAA (0.40) | — | |
| SCHEMBL9530731 | 0.71 | TSHR (0.33) | POLBCHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL9530208 | 0.71 | TSHR (0.33) | POLBCHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL11048580 | 0.70 | MT-CO2 (0.57) | POLBALOX5 | |
| SCHEMBL14599844 | 0.69 | CHRM2 (0.37) | POLBCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL411121 | 0.69 | CHRM2 (0.37) | POLBCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL12052490 | 0.69 | CHRM2 (0.37) | POLBCHRM2CHRM1MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160128-A | Tritioacetylating reagents and processes for preparation thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-12 | — | — | US | claimed |
| US-6160128-A | Tritioacetylating reagents and processes for preparation thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-12 | — | — | US | disclosed |