SCHEMBL7759035

SCHEMBL7759035

NCCCC[C@H](NC(=O)C1OC1C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MC4R P32245 2/20 0.44
MC5R P33032 1/20 0.44
MC3R P41968 1/20 0.44
FURIN P09958 1/20 0.43
F2 P00734 1/20 0.42
HRH1 P35367 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7763498 0.99 MC4R (0.43) MC4RMC5RMC3RFURINF2
SCHEMBL7759040 0.87 CPB2 (0.46)
Hydrochloric Acid SCHEMBL7761841 0.84 F2 (0.45) MC4RMC5RMC3RF2
SCHEMBL7763541 0.80 MMP9 (0.49) F2
SCHEMBL7765729 0.78 CAPN1 (0.52)
SCHEMBL6070379 0.78 CAPN1 (0.52)
SCHEMBL7765736 0.78 CAPN1 (0.52)
SCHEMBL6070071 0.78 CAPN1 (0.52)
Hydrochloric Acid SCHEMBL9090223 0.78 MC4R (0.45) MC4RMC5RMC3R
SCHEMBL7762774 0.78 NTMT1 (0.52) MC4RMC5RMC3RFURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808839-B1 EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME TAIHO PHARMACEUTICAL CO LTD (JP) 2001-05-23 EP disclosed
EP-0808839-A1 EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME TAIHO PHARMACEUTICAL CO., LTD. (JP) 1997-11-26 EP disclosed