Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 8/20 | 0.41 |
| ▸ | REN | P00797 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759104 | 1.00 | DPP4 (0.42) | DPP4DPP8DPP9ACEREN | |
| SCHEMBL4595209 | 0.96 | DPP4 (0.44) | DPP4DPP8DPP9ACEREN | |
| SCHEMBL4595206 | 0.96 | DPP4 (0.44) | DPP4DPP8DPP9ACEREN | |
| SCHEMBL5734357 | 0.96 | DPP4 (0.44) | DPP4DPP8DPP9ACEREN | |
| SCHEMBL31618960 | 0.95 | LTA4H (0.38) | DPP4DPP8DPP9ACELTA4H | |
| SCHEMBL10454951 | 0.92 | TRHR (0.43) | DPP4DPP8DPP9ACEREN | |
| SCHEMBL10454953 | 0.92 | TRHR (0.43) | DPP4DPP8DPP9ACEREN | |
| SCHEMBL29630526 | 0.89 | TRHR (0.41) | ACEACE2 | |
| SCHEMBL29590456 | 0.89 | TRHR (0.41) | ACEACE2 | |
| SCHEMBL678488 | 0.89 | DPP4 (0.42) | DPP4DPP8DPP9ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068114-A1 | NOVEL PEPTIDES WITH ANTI-HYPERTENSIVE ACTIVITY | MONSANTO COMPANY (US) | 2001-09-20 | — | — | WO | disclosed |