Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22497560 | 0.77 | LTB4R (0.41) | PTPN1PTPN6BACE1LDHALDHB | |
| SCHEMBL7039237 | 0.76 | BACE1 (0.45) | PTPN1PTPN6BACE1LTB4RLTB4R2 | |
| SCHEMBL2879317 | 0.72 | BACE1 (0.50) | PTPN1PTPN6BACE1LTB4RLTB4R2 | |
| SCHEMBL28700316 | 0.70 | BACE1 (0.42) | PTPN1PTPN6BACE1LTB4RLTB4R2 | |
| SCHEMBL8641643 | 0.70 | CNR1 (0.50) | PTPN1PTPN6BACE1PTPN2PDE4B | |
| SCHEMBL27681638 | 0.69 | BACE1 (0.50) | BACE1LTB4RLTB4R2PDE4BPPARG | |
| SCHEMBL4633167 | 0.68 | HNF4A (0.46) | PTPN1PTPN6BACE1PDE4BPELI1 | |
| SCHEMBL4633168 | 0.68 | HNF4A (0.46) | PTPN1PTPN6BACE1PDE4BPELI1 | |
| SCHEMBL30937373 | 0.68 | HK2 (0.43) | BACE1LTB4RLTB4R2PDE4BKDM4E | |
| SCHEMBL10435692 | 0.67 | BACE1 (0.42) | BACE1ESR1LTB4RLTB4R2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001026537-A | ANTIANXIETY MEDICINE | TSUMURA & CO | 2001-01-30 | — | — | JP | disclosed |