Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707821 | 0.84 | HRH1 (0.40) | RIPK1TAAR1CACNA1FCHRM2CHRM1 | |
| SCHEMBL28914813 | 0.79 | TAAR1 (0.44) | RIPK1TAAR1AOC3TRPA1 | |
| SCHEMBL927508 | 0.79 | ESR1 (0.33) | — | |
| SCHEMBL3400155 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL5664123 | 0.77 | RIPK1 (0.63) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL1019329 | 0.76 | RIPK1 (0.52) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL2418232 | 0.74 | RIPK1 (0.53) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL21322418 | 0.74 | TAAR1 (0.56) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL20427677 | 0.74 | RIPK1 (0.53) | RIPK1TAAR1AOC3TRPA1CACNA1F | |
| SCHEMBL2773877 | 0.73 | RIPK1 (0.30) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085022-A1 | A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds | Dow Corning Asia, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6060620-A | Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds | DOW CORNING ASIA, LTD. (JP) | 2000-05-09 | — | — | US | disclosed |
| EP-0652246-B1 | Base-catalysed preparation of an hydrogen containing polyorganosiloxane | WACKER CHEMIE GMBH (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0652246-A1 | Base-catalysed preparation of an hydrogen containing polyorganosiloxane | Wacker-Chemie GmbH (DE) | 1995-05-10 | — | — | EP | disclosed |