Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5708512 | 0.99 | HRH3 (0.39) | HRH3ALDH1A1KDM4EADRB2MEN1 | |
| SCHEMBL8637445 | 0.83 | HRH1 (0.46) | HRH3SIGMAR1 | |
| SCHEMBL4322788 | 0.82 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL8639270 | 0.81 | LTA4H (0.44) | HRH3SIGMAR1TSHR | |
| SCHEMBL8641764 | 0.79 | HRH3 (0.50) | HRH3SIGMAR1 | |
| SCHEMBL8644129 | 0.78 | LMNA (0.41) | HRH3ALDH1A1ADRB2 | |
| SCHEMBL8147094 | 0.78 | ATM (0.44) | HRH3KDM4E | |
| SCHEMBL7246918 | 0.77 | CARM1 (0.40) | — | |
| SCHEMBL11277901 | 0.76 | HRH3 (0.42) | HRH3 | |
| SCHEMBL8640497 | 0.76 | SPHK2 (0.50) | HRH3ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082319-A1 | BENZOCARBAZOL AND INDENOINOLE DERIVED ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999058524-A1 | BENZOCARBAZOLE AND INDENOINDOLE DERIVED ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |