Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759823 | 0.92 | SIGMAR1 (0.48) | CCR3SIGMAR1DRD2KMT2A | |
| SCHEMBL9230596 | 0.89 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL8110476 | 0.85 | SIGMAR1 (0.61) | CCR3SIGMAR1 | |
| SCHEMBL8117012 | 0.84 | SIGMAR1 (0.59) | SIGMAR1DRD2KMT2A | |
| SCHEMBL9449991 | 0.83 | SIGMAR1 (0.47) | SIGMAR1KDM4EALDH1A1HTR2BKMT2A | |
| SCHEMBL9232860 | 0.83 | SIGMAR1 (0.55) | CCR3SIGMAR1KDM4EALDH1A1HTR7 | |
| SCHEMBL8948173 | 0.82 | SIGMAR1 (0.46) | SIGMAR1DRD2 | |
| SCHEMBL9449597 | 0.81 | SIGMAR1 (0.55) | SIGMAR1KDM4E | |
| SCHEMBL8948263 | 0.81 | SIGMAR1 (0.48) | SIGMAR1HTR7DRD2 | |
| SCHEMBL7756765 | 0.81 | SIGMAR1 (0.58) | SIGMAR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | claimed |
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |