Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230596 | 0.92 | SIGMAR1 (0.54) | SIGMAR1CYP1A2CYP2D6TMEM97POLB | |
| SCHEMBL7759823 | 0.88 | SIGMAR1 (0.48) | SIGMAR1POLBHTR1A | |
| SCHEMBL7756722 | 0.84 | SIGMAR1 (0.53) | SIGMAR1CYP1A2CYP2D6TMEM97POLB | |
| SCHEMBL7759855 | 0.81 | CCR3 (0.58) | SIGMAR1HTR7 | |
| SCHEMBL9449597 | 0.80 | SIGMAR1 (0.55) | SIGMAR1CYP1A2CYP2D6TMEM97HTR1A | |
| SCHEMBL7762764 | 0.79 | KDM4E (0.55) | SIGMAR1TMEM97SMN1; SMN2HTR1A | |
| SCHEMBL9232860 | 0.78 | SIGMAR1 (0.55) | SIGMAR1TMEM97POLBHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL9449928 | 0.76 | HTR1A (0.51) | SIGMAR1TMEM97POLBHTR1A | |
| SCHEMBL9449807 | 0.76 | DRD2 (0.46) | CYP1A2CYP2D6HTR1A | |
| SCHEMBL7759833 | 0.76 | SIGMAR1 (0.51) | SIGMAR1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | claimed |
| CN-1111626-A | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1995-11-15 | — | — | CN | claimed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | claimed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |