Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760151 | 0.84 | HSD17B10 (0.40) | LMNAHSD17B10CES2ALDH1A1FDPS | |
| SCHEMBL27571528 | 0.80 | HSD17B10 (0.38) | LMNAHSD17B10CES2ALDH1A1FDPS | |
| SCHEMBL7757124 | 0.77 | CES2 (0.39) | LMNAHSD17B10CES2FDPS | |
| SCHEMBL7757136 | 0.75 | CES2 (0.47) | HSD17B10CES2FDPS | |
| SCHEMBL19971163 | 0.75 | — | — | |
| SCHEMBL7761953 | 0.72 | LMNA (0.32) | LMNAHSD17B10 | |
| SCHEMBL7760148 | 0.71 | CES2 (0.42) | HSD17B10CES2FDPS | |
| SCHEMBL7761145 | 0.71 | CYP2C9 (0.34) | LMNAHSD17B10 | |
| SCHEMBL7762248 | 0.71 | LMNA (0.32) | LMNAHSD17B10 | |
| SCHEMBL8531695 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |