Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LIPA | P38571 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757158 | 0.89 | LMNA (0.37) | CYP2C9HSD11B1MAPTLMNAMAPK1 | |
| SCHEMBL7757145 | 0.88 | CES2 (0.40) | MAPTLMNAMAPK1HTTHSD17B10 | |
| SCHEMBL7760151 | 0.80 | HSD17B10 (0.40) | LMNAHSD17B10 | |
| SCHEMBL27571528 | 0.76 | HSD17B10 (0.38) | THRBLMNAHSD17B10 | |
| SCHEMBL7757124 | 0.72 | CES2 (0.39) | LMNAHSD17B10 | |
| SCHEMBL14795277 | 0.71 | THRA (0.42) | CYP2C9HSD11B1THRATHRBLMNA | |
| SCHEMBL30281253 | 0.71 | TDP1 (0.38) | HSD11B1THRATHRBLMNATDP1 | |
| SCHEMBL14795141 | 0.71 | THRA (0.42) | CYP2C9HSD11B1THRATHRBLMNA | |
| SCHEMBL14795101 | 0.71 | THRA (0.42) | CYP2C9HSD11B1THRATHRBLMNA | |
| SCHEMBL7757136 | 0.71 | CES2 (0.47) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |