SCHEMBL7760372

SCHEMBL7760372

C#CC[C@]1(n2cc(N)c(=O)[nH]c2=O)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TK1 P04183 4/20 0.35
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALOX12 P18054 1/20 0.33
ADRA1A P35348 1/20 0.33
TK2 O00142 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PYGM P11217 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1941867 0.87 TK1 (0.41) TK1LMNATSHRBLMPMP22
SCHEMBL15321521 0.85 TK1 (0.34) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL28836964 0.84 TK1 (0.34) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL3485976 0.81 P2RY6 (0.41)
SCHEMBL5500343 0.80 DNMT1 (0.33)
SCHEMBL30241241 0.76 LMNA (0.49) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL1517629 0.76 TK1 (0.44) TK1LMNAADRA1ATSHRBLM
SCHEMBL14388593 0.75 TK1 (0.43) TK1LMNAADRA1ATSHRBLM
SCHEMBL27436150 0.75 TK1 (0.43) TK1LMNAADRA1ATSHRBLM
SCHEMBL28114849 0.74 DNMT1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3108010-A1 SAMPLE PREPARATION METHOD Oxford Nanopore Technologies Limited (GB) 2016-12-28 EP disclosed
WO-2015124935-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-08-27 WO disclosed
CN-1345745-A Novel polypeptide-RCC1 protein 13.20 and polynucleotide for encoding said polypeptide SHANGHAI BIOWINDOW GENE DEV (CN) 2002-04-24 CN disclosed
CN-1328017-A Polypeptide-human TNFR/NGFR protein 12 containing cytochrome C structure domain and polynucleotide for coding it BODE GENE DEV CO LTD SHANGHAI (CN) 2001-12-26 CN disclosed
CN-1328018-A Polypeptide-human TNFR/NGFR protein 10 containing cytochrome C structure domain and polynucleotide for coding it BODE GENE DEV CO LTD SHANGHAI (CN) 2001-12-26 CN disclosed
CN-1327062-A New polypeptide-human protein phoshatase 24.53 and polynucleotide for encoding such polypeptide BODE GENE DEV CO LTD SHANGHAI (CN) 2001-12-19 CN disclosed
CN-1327063-A New polypeptide-human protein phosphatase 11.66 and polynucleotide for encoding such polypeptide BODE GENE DEV CO LTD SHANGHAI (CN) 2001-12-19 CN disclosed
WO-2001092315-A1 A NOVEL POLYPEPTIDE, A HUMAN SPLICING PROTEIN 10.56 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE SHANGHAI BIOWINDOW GENE DEVELOPMENT INC. (CN) 2001-12-06 WO disclosed
CN-1321764-A Novel polypeptide-human phosphatidase 9 ad polynucleotide for coding this polypeptide BODE GENE DEV CO LTD SHANGHAI (CN) 2001-11-14 CN disclosed
CN-1321686-A Novel polypeptide-human myb protein 41 and polynucleotide for coding this polypeptide BODE GENE DEV CO LTD SHANGHAI (CN) 2001-11-14 CN disclosed
CN-1314360-A New polypeptide-FAT 24 and polynucleotide for coding such polypeptide BODE GENE DEV CO LTD SHANGHAI (CN) 2001-09-26 CN disclosed
CN-1314478-A New polypeptide-human periodical protein dependent kinase 14 and polynucleotide for coding such polypeptide BODE GENE DEV CO LTD SHANGHAI (CN) 2001-09-26 CN disclosed
CN-1311250-A New polypeptide-human frontotemporal bone dementia and paralysis agitans (FTDP-17) relative protein 29 and polynucleotide for coding such polypeptide BODE GENE DEV CO LTD SHANGHAI (CN) 2001-09-05 CN disclosed
CN-1307031-A Polypeptide-human zinc finger protein 19 and polynucleotide for coding said polypeptide BODAO GENE TECH CO LTD (CN) 2001-08-08 CN disclosed
CN-1307106-A Polypeptide-human type II aminoacyl-tRNA synthetase 75 and polynucleotide for coding said polypeptide BODAO GENE TECH CO LTD (CN) 2001-08-08 CN disclosed
CN-1307107-A Polypeptide-DNA polymerase III 18 and polynucleotide for coding said polypeptide BODAO GENE TECH CO LTD (CN) 2001-08-08 CN disclosed
CN-1301822-A New polypeptide-DNA methylating enzyme 13 and polynucleotide coding such polypeptide BODE GENE DEV CO LTD SHANGHAI (CN) 2001-07-04 CN disclosed
CN-1301762-A New polypeptide-human lissencephalic protein 43 and polynucleotide coding such polypeptide UNIV FUDAN (CN) 2001-07-04 CN disclosed
CN-1301764-A New polypeptide-human zinc-finger protein 25 and polynucleotide coding such polypeptide UNIV FUDAN (CN) 2001-07-04 CN disclosed
CN-1300823-A Polypeptide-DNA ligase 10 and polynucleotide for coding this polypeptide UNIV FUDAN (CN) 2001-06-27 CN disclosed