Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 3/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114849 | 0.89 | DNMT1 (0.32) | DNMT1ADRB1 | |
| SCHEMBL28805006 | 0.83 | PDE3A (0.43) | DNMT1ADRB1PDE4DPDE3ASLC29A1 | |
| SCHEMBL886859 | 0.81 | POLG (0.41) | — | |
| SCHEMBL7760372 | 0.80 | TK1 (0.35) | — | |
| SCHEMBL1941867 | 0.72 | TK1 (0.41) | — | |
| SCHEMBL5976411 | 0.71 | PDE4D (0.35) | DNMT1ADRB1PDE4DPDE3ASLC29A1 | |
| SCHEMBL9446590 | 0.71 | PDE4D (0.35) | DNMT1ADRB1PDE4DPDE3ASLC29A1 | |
| SCHEMBL7517670 | 0.71 | PDE3A (0.43) | DNMT1ADRB1PDE4DPDE3ASLC29A1 | |
| SCHEMBL4971926 | 0.70 | PDE3A (0.46) | DNMT1ADRB1PDE4DPDE3ASLC29A1 | |
| SCHEMBL15321521 | 0.70 | TK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451318-A4 | COMPILATIONS OF NUCLEIC ACIDS AND ARRAYS AND METHODS OF USING THEM | PERKINELMER LAS INC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1451318-A1 | COMPILATIONS OF NUCLEIC ACIDS AND ARRAYS AND METHODS OF USING THEM | Spectral Genomics, Inc (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003091426-A1 | COMPILATIONS OF NUCLEIC ACIDS AND ARRAYS AND METHODS OF USING THEM | SPECTRAL GENOMICS, INC. (US) | 2003-11-06 | — | — | WO | disclosed |