SCHEMBL28114849

SCHEMBL28114849

C#CC[C@]1(n2cc(C)c(N)nc2=O)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 3/20 0.32
ADRB1 P08588 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5500343 0.89 DNMT1 (0.33) DNMT1ADRB1
SCHEMBL28805006 0.81 PDE3A (0.43) DNMT1ADRB1
SCHEMBL9446590 0.81 PDE4D (0.35) DNMT1ADRB1
SCHEMBL1941867 0.79 TK1 (0.41)
SCHEMBL8415348 0.76 DNMT1 (0.32) DNMT1
SCHEMBL7760372 0.74 TK1 (0.35)
SCHEMBL6394687 0.74 RNASE1 (0.32) DNMT1ADRB1
SCHEMBL8581452 0.73 DNMT1 (0.31) DNMT1
SCHEMBL1684840 0.72 DNMT1 (0.34) DNMT1ADRB1
SCHEMBL234386 0.72 LMNA (0.34) DNMT1ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105264088-B Improve the dynamic range of multiple epitopes in identification of cell 豪夫迈·罗氏有限公司 2018-12-28 CN disclosed
CN-103703143-B Method for identifying multiple epitopes in a cell 爱普瑞斯生物公司 2016-12-14 CN disclosed