Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969307 | 0.94 | TSHR (0.34) | TSHRTDP1ALDH1A1 | |
| SCHEMBL705365 | 0.87 | ADRB2 (0.35) | TSHRALDH1A1DNM1ADRB2ADRB1 | |
| SCHEMBL706696 | 0.87 | ADRB2 (0.35) | TSHRALDH1A1DNM1ADRB2ADRB1 | |
| SCHEMBL703595 | 0.85 | ADRB2 (0.36) | TSHRALDH1A1DNM1ADRB2ADRB1 | |
| SCHEMBL2552187 | 0.82 | DNM1 (0.39) | TSHRALDH1A1DNM1ADRB2ADRB1 | |
| SCHEMBL56371 | 0.81 | THRB (0.32) | TSHRTDP1 | |
| SCHEMBL375870 | 0.80 | DNM1 (0.31) | DNM1ADRB2ADRB1ADRB3 | |
| SCHEMBL3917311 | 0.80 | — | — | |
| SCHEMBL28373433 | 0.79 | DNM1 (0.30) | DNM1 | |
| SCHEMBL209603 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705838-B1 | Process for the preparation of silane polysulfides | CROMPTON CORP (US) | 2001-05-23 | — | — | EP | disclosed |
| US-5596116-A | Process for the preparation of silane polysulfides | OSI SPECIALTIES, INC. (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0705838-A2 | Process for the preparation of silane polysulfides | OSi SPECIALTIES, INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5489701-A | REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION | OSI SPECIALTIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5466848-A | Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane | OSI SPECIALTIES, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5399739-A | Method of making sulfur-containing organosilanes | WRIGHT CHEMICAL CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |
| US-4129585-A | NO FORMATION OF HYDROGEN SULFIDE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1978-12-12 | — | — | US | disclosed |