SCHEMBL375870

SCHEMBL375870

CCCCOC(OCCCC)[SiH2]CCCS

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.31
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30
ADRB3 P13945 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375556 0.92 DNM1 (0.40) DNM1
SCHEMBL4539609 0.92 DNM1 (0.40) DNM1
SCHEMBL375529 0.90
SCHEMBL705365 0.87 ADRB2 (0.35) DNM1ADRB2ADRB1ADRB3
SCHEMBL706696 0.87 ADRB2 (0.35) DNM1ADRB2ADRB1ADRB3
SCHEMBL703595 0.85 ADRB2 (0.36) DNM1ADRB2ADRB1ADRB3
SCHEMBL2552187 0.82 DNM1 (0.39) DNM1ADRB2ADRB1ADRB3
SCHEMBL375562 0.81 THRB (0.32)
SCHEMBL7760600 0.80 TSHR (0.39) DNM1ADRB2ADRB1ADRB3
SCHEMBL29211233 0.79 THRB (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 US claimed
US-20060252952-A1 Process for preparing mercaptoorganyl (alkoxysilanes) DEGUSSA AG (DE) 2006-11-09 US claimed
US-12139635-B2 Coatings for waterproofing electronic components HENKEL AG & CO. KGAA (DE) 2024-11-12 US disclosed
US-20220002559-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2022-01-06 US disclosed
WO-2020197963-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2020-10-01 WO disclosed
US-10563047-B2 Rubber composition and pneumatic tire including the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2020-02-18 US disclosed
EP-3156444-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME YOKOHAMA RUBBER CO LTD (JP) 2019-07-24 EP disclosed
EP-2891679-B9 RUBBER COMPOSITION FOR TIRE TREADS YOKOHAMA RUBBER CO LTD (JP) 2018-09-12 EP disclosed
US-9790306-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-10-17 US disclosed
EP-2891679-B1 RUBBER COMPOSITION FOR TIRE TREADS YOKOHAMA RUBBER CO LTD (JP) 2017-09-27 EP disclosed
US-20170130036-A1 Rubber Composition and Pneumatic Tire Including the Same THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-05-11 US disclosed
US-7019160-B2 Process for the preparation of (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-03-28 US disclosed
EP-1637535-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa GmbH (DE) 2006-03-22 EP disclosed
US-20060052622-A1 Process for the preparation of mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2006-03-09 US disclosed
US-20060052621-A1 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2006-03-09 US disclosed
US-6995280-B2 Process for preparing (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-02-07 US disclosed
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
EP-1538152-A1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen Degussa AG (DE) 2005-06-08 EP disclosed
EP-1529782-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa AG (DE) 2005-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes ADH1C, ADH1A, MPST DNM1 2435/4885ADRB2 1933/4885ADRB1 2168/4885
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes MPST, ADH1A, ADH1C DNM1 3260/4885ADRB2 1713/4885ADRB1 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.