Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761689 | 0.81 | FAAH (0.50) | MAPTFAAHALDH1A1LMNATP53 | |
| SCHEMBL7761692 | 0.80 | POLB (0.47) | FAAHALDH1A1KMT2AMAPK1MEN1 | |
| SCHEMBL7763284 | 0.80 | MAPK1 (0.53) | MAPTFAAHALDH1A1LMNATP53 | |
| SCHEMBL7761944 | 0.75 | KMT2A (0.67) | MAPTKMT2AL3MBTL1MEN1PKM | |
| SCHEMBL7300289 | 0.75 | MAPT (0.62) | MAPTALDH1A1LMNAKMT2AL3MBTL1 | |
| SCHEMBL651830 | 0.74 | PKM (0.76) | FAAHALDH1A1LMNATP53KMT2A | |
| SCHEMBL5458965 | 0.74 | MAPT (0.79) | MAPTFAAHALDH1A1LMNAKMT2A | |
| SCHEMBL654167 | 0.73 | SMN1; SMN2 (0.60) | ALDH1A1KMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL4680684 | 0.73 | SMN1; SMN2 (0.52) | MAPTALDH1A1PKMSMN1; SMN2POLB | |
| SCHEMBL7760879 | 0.73 | MAPT (0.53) | MAPTALDH1A1KMT2AMAPK1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |