Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756878 | 0.86 | KDM4E (0.58) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL7756925 | 0.82 | NPC1 (0.49) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL7760034 | 0.81 | MAPT (0.51) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL8366816 | 0.80 | HDAC1 (0.58) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL7760885 | 0.79 | HIF1A (0.78) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL17079633 | 0.73 | ITGB3 (0.66) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL5594906 | 0.72 | CFD (0.74) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL12725528 | 0.71 | HIF1A (0.48) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL12725538 | 0.71 | HIF1A (0.53) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL1505239 | 0.71 | ALDH1A1 (0.68) | MEN1KMT2AKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |