SCHEMBL7130439

SCHEMBL7130439

O=C(c1ccccc1C(=O)N1CCN(Cc2ccccc2)CC1)N1CCN(Cc2ccccc2)CC1

nearest known ligand 0.76

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.72
ALDH1A1 P00352 4/20 0.71
KDM4E B2RXH2 1/20 0.71
SMN1; SMN2 Q16637 3/20 0.69
KMT2A Q03164 2/20 0.69
MEN1 O00255 1/20 0.69
TSHR P16473 1/20 0.69
MAPK1 P28482 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
MAPK14 Q16539 2/20 0.67
HTT P42858 2/20 0.66
CYP1A2 P05177 1/20 0.66
CYP2C19 P33261 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10789644 0.88 LMNA (0.62) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL9645824 0.86 KDM4E (0.94) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL1019998 0.86 KDM4E (0.94) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL223297 0.85 CYP2C9 (0.65) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL7760912 0.84 MEN1 (0.74) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL12833232 0.84 LMNA (0.58) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL10825084 0.84 ALDH1A1 (0.70) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL2850013 0.84 ALDH1A1 (0.70) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL27791391 0.84 ALDH1A1 (0.70) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL14459990 0.83 LMNA (0.64) LMNAALDH1A1KDM4ESMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed