Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045299 | 0.85 | PAOX (0.40) | SMN1; SMN2KMT2AALDH1A1CHRM3POLB | |
| SCHEMBL3051235 | 0.83 | HRH3 (0.42) | SMN1; SMN2ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL1033434 | 0.82 | KEAP1 (0.54) | HPGDDUSP3SMN1; SMN2KEAP1NPSR1 | |
| SCHEMBL3049699 | 0.79 | HRH3 (0.45) | SMN1; SMN2ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL18024079 | 0.78 | ALDH1A1 (0.50) | HPGDDUSP3SMN1; SMN2KEAP1NPSR1 | |
| SCHEMBL18024015 | 0.78 | ALDH1A1 (0.50) | HPGDDUSP3SMN1; SMN2KEAP1NPSR1 | |
| SCHEMBL12250550 | 0.78 | KEAP1 (0.48) | HPGDDUSP3SMN1; SMN2KEAP1NPSR1 | |
| SCHEMBL3054073 | 0.77 | KCNH2 (0.56) | SIGMAR1 | |
| SCHEMBL21573998 | 0.76 | RAB9A (0.41) | HPGDDUSP3SMN1; SMN2KEAP1NPSR1 | |
| SCHEMBL22997580 | 0.75 | KEAP1 (0.50) | HPGDDUSP3SMN1; SMN2KEAP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098903-A1 | NOVEL METHOD FOR PREPARING CYCLOSPORIN DERIVATIVES | Aventis Pharma S.A. (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-1999067280-A1 | NOVEL METHOD FOR PREPARING CYCLOSPORIN DERIVATIVES | AVENTIS PHARMA S.A. (FR) | 1999-12-29 | — | — | WO | disclosed |