Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPA | P38571 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281253 | 0.76 | TDP1 (0.38) | LIPATDP1ALOX5HSD11B1THRA | |
| SCHEMBL7760136 | 0.73 | LMNA (0.33) | LIPA | |
| SCHEMBL14795141 | 0.71 | THRA (0.42) | LIPATDP1ALOX5HSD11B1THRA | |
| SCHEMBL14795277 | 0.71 | THRA (0.42) | LIPATDP1ALOX5HSD11B1THRA | |
| SCHEMBL14795101 | 0.71 | THRA (0.42) | LIPATDP1ALOX5HSD11B1THRA | |
| SCHEMBL7763686 | 0.71 | CES2 (0.35) | — | |
| SCHEMBL7761964 | 0.69 | CES2 (0.42) | — | |
| SCHEMBL7761139 | 0.68 | HSD11B1 (0.34) | LIPATDP1ALOX5HSD11B1THRA | |
| SCHEMBL31119442 | 0.67 | — | — | |
| SCHEMBL7761957 | 0.67 | LIPA (0.31) | LIPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |