Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Famoxadone SCHEMBL14128616 | 0.89 | MMP2 (0.42) | LMNAMAPK1HTTTSHRSMN1; SMN2 | |
| Famoxadone SCHEMBL63351 | 0.89 | MMP2 (0.42) | LMNAMAPK1HTTTSHRSMN1; SMN2 | |
| Famoxadone SCHEMBL673443 | 0.89 | MMP2 (0.42) | LMNAMAPK1HTTTSHRSMN1; SMN2 | |
| Famoxadone SCHEMBL17293878 | 0.88 | MMP2 (0.41) | LMNAMAPK1HTTTSHRSMN1; SMN2 | |
| SCHEMBL27339346 | 0.88 | PGR (0.39) | LMNAMAPK1HTTTSHRHCAR2 | |
| SCHEMBL9370594 | 0.88 | PGR (0.39) | LMNAMAPK1HTTTSHRHCAR2 | |
| SCHEMBL9869697 | 0.85 | CYP1A2 (0.42) | LMNAHTTHCAR2MAPTHPGD | |
| Famoxadone SCHEMBL28139781 | 0.84 | MMP1 (0.40) | MAPK1SMN1; SMN2RAB9AHPGDF13A1 | |
| Famoxadone SCHEMBL27502240 | 0.84 | MMP2 (0.38) | HTTMAPTHPGDADAM17MEN1 | |
| Famoxadone SCHEMBL6060933 | 0.80 | MMP2 (0.36) | LMNAMAPK1HTTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092712-A1 | Process for preparing fungicidal oxazolidinones and imidazolinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-04-18 | — | — | EP | disclosed |