Famoxadone

Famoxadone

SCHEMBL6060933

CC1(c2ccc(Oc3ccccc3)cc2)OC(=O)N(Nc2ccccc2)C1=O.Cc1cc(=O)[nH]o1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.36
MMP9 P14780 3/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
MMP13 P45452 1/20 0.36
LMNA P02545 3/20 0.32
AKR1C3 P42330 2/20 0.32
MMP1 P03956 1/20 0.32
ADAM17 P78536 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
ACHE P22303 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Famoxadone SCHEMBL63351 0.87 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
Famoxadone SCHEMBL14128616 0.87 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
Famoxadone SCHEMBL673443 0.87 MMP2 (0.42) MMP2MMP9MMP3MMP8MMP13
Famoxadone SCHEMBL17293878 0.86 MMP2 (0.41) MMP2MMP9MMP3MMP8MMP13
Famoxadone SCHEMBL28139781 0.82 MMP1 (0.40) MMP2MMP9MMP3MMP8MMP13
Famoxadone SCHEMBL27502240 0.82 MMP2 (0.38) MMP2MMP9MMP3MMP8MMP13
SCHEMBL9370594 0.82 PGR (0.39) MMP2MMP9MMP3MMP8MMP13
SCHEMBL27339346 0.82 PGR (0.39) MMP2MMP9MMP3MMP8MMP13
Famoxadone SCHEMBL28267474 0.82 LMNA (0.36) MMP2MMP9MMP3MMP8MMP13
SCHEMBL7761159 0.80 LMNA (0.39) MMP2MMP9MMP3MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1656019-A1 USE OF ALCOHOL-OXYALKYLATES IN THE FORM OF ADJUVANTS FOR BENZAMIDOXIME GUNGICIDAL DERIVATIVES, APPROPRIATE AGENTS AND KITS BASF AKTIENGESELLSCHAFT (DE) 2006-05-17 EP disclosed
WO-2005015998-A1 USE OF ALCOHOL-OXYALKYLATES IN THE FORM OF ADJUVANTS FOR BENZAMIDOXIME GUNGICIDAL DERIVATIVES, APPROPRIATE AGENTS AND KITS BASF AKTIENGESELLSCHAFT (DE) 2005-02-24 WO disclosed