SCHEMBL7761332

SCHEMBL7761332

C[SiH2]OC(=O)CCCCCCCCCCCCCCCCCO[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.36
ALDH1A1 P00352 2/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
DNM1 Q05193 1/20 0.31
LMNA P02545 3/20 0.31
TSHR P16473 1/20 0.30
HTR2C P28335 1/20 0.30
PAM P19021 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7058911 0.79 ALDH1A1 (0.55) DGKAALDH1A1PRSS1PRSS2PRSS3
SCHEMBL7060130 0.79 ALDH1A1 (0.55) DGKAALDH1A1PRSS1PRSS2PRSS3
SCHEMBL16294270 0.79 TSHR (0.54) DGKAALDH1A1LMNATSHR
SCHEMBL16295170 0.79 DGKA (0.39) DGKAALDH1A1PRSS1PRSS2PRSS3
SCHEMBL18038087 0.79 TSHR (0.54) DGKAALDH1A1LMNATSHR
SCHEMBL16294179 0.79 TSHR (0.54) DGKAALDH1A1LMNATSHR
SCHEMBL7759649 0.78 DGKA (0.38) DGKAALDH1A1PRSS1PRSS2PRSS3
SCHEMBL7051617 0.76 DGKA (0.41) DGKAALDH1A1PRSS1PRSS2PRSS3
SCHEMBL13044430 0.76 DGKA (0.50) DGKAALDH1A1DNM1TSHRPAM
SCHEMBL7060615 0.76 DGKA (0.41) DGKAALDH1A1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed