Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763284 | 0.82 | MAPK1 (0.53) | FAAHKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7760048 | 0.81 | MAPT (0.50) | FAAHKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL654167 | 0.80 | SMN1; SMN2 (0.60) | KMT2AMEN1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL8366816 | 0.79 | HDAC1 (0.58) | KMT2AMEN1ALDH1A1HIF1APKM | |
| SCHEMBL7760053 | 0.79 | POLB (0.50) | KMT2AMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL651830 | 0.76 | PKM (0.76) | FAAHKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5458965 | 0.76 | MAPT (0.79) | FAAHKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL30384496 | 0.73 | MAPT (0.53) | KMT2AMAPTALDH1A1TP53MAPK1 | |
| SCHEMBL2418935 | 0.73 | MAPT (0.53) | KMT2AMAPTALDH1A1TP53MAPK1 | |
| SCHEMBL7760885 | 0.73 | HIF1A (0.78) | KMT2AMEN1MAPTALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |
| US-6541479-B1 | Derivatives of thiosalicylic acid and o-aminobenzoic acid | MASSACHUSETTS COLLEGE OF PHARMACY | 2003-04-01 | — | — | US | disclosed |