SCHEMBL7761783

SCHEMBL7761783

C=C1CC(C)N(Cc2ccccc2)C1=O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
ALOX12 P18054 1/20 0.46
MAPK1 P28482 1/20 0.46
EHMT2 Q96KQ7 1/20 0.45
ACHE P22303 1/20 0.44
BRD4 O60885 1/20 0.43
P2RX7 Q99572 1/20 0.43
CACNA1G O43497 1/20 0.42
CACNA1H O95180 1/20 0.42
CACNA1I Q9P0X4 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SMO Q99835 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21538655 0.80 LMNA (0.50) LMNAALOX12MAPK1EHMT2ACHE
SCHEMBL18772595 0.78 EHMT2 (0.46) LMNAALOX12MAPK1EHMT2ACHE
SCHEMBL7767457 0.76 EHMT2 (0.38) MAPK1EHMT2ALDH1A1MEN1KMT2A
SCHEMBL19370604 0.74 LMNA (0.52) LMNAALOX12MAPK1EHMT2BRD4
SCHEMBL7766819 0.74 MEN1 (0.36) EHMT2ALDH1A1MEN1KMT2A
SCHEMBL7765809 0.74 EHMT2 (0.42) LMNAMAPK1EHMT2ALDH1A1MEN1
SCHEMBL17426060 0.73 EHMT2 (0.51) EHMT2BRD4ALDH1A1SMO
SCHEMBL11495615 0.73 HCRTR1 (0.45) LMNAALOX12MAPK1CACNA1GCACNA1H
SCHEMBL7769361 0.72 CYP1A2 (0.40) EHMT2ALDH1A1MEN1KMT2A
SCHEMBL7765772 0.72 SDCBP (0.38) MAPK1EHMT2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101609255-A Curing combination for nanometer stamping, pattern formation method FUJI PHOTO FILM CO LTD (JP) 2009-12-23 CN disclosed
EP-0723967-B1 Organometallic compounds and polymers made therefrom ATOCHEM NORTH AMERICA ELF (US) 2001-04-11 EP disclosed
US-5786392-A SUSTAINED RELEASE; MARINE ANTIFOULING AGENT ATOFINA CHEMICALS, INC., A CORP. OF PENNSYLVANIA 1998-07-28 US disclosed
US-5637745-A MARINE ANTIFOULING AGENT; SUSTAINED RELEASE ELF ATOCHEM NORTH AMERICA, INC. (US) 1997-06-10 US disclosed
EP-0723967-A1 Organometallic compounds and polymers made therefrom ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-07-31 EP disclosed