Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 1/20 | 0.38 |
| ▸ | SDC2 | P34741 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766806 | 0.78 | CRBN (0.40) | SDCBPSDC2MEN1KMT2AMAPT | |
| SCHEMBL7765809 | 0.76 | EHMT2 (0.42) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL7766819 | 0.73 | MEN1 (0.36) | MEN1KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL7764884 | 0.73 | CRBN (0.36) | SDCBPSDC2MAPT | |
| SCHEMBL7764955 | 0.72 | EHMT2 (0.38) | MEN1KMT2AMAPTALDH1A1EHMT2 | |
| SCHEMBL7761783 | 0.72 | LMNA (0.46) | MEN1KMT2AALDH1A1MAPK1EHMT2 | |
| SCHEMBL7769361 | 0.71 | CYP1A2 (0.40) | MEN1KMT2ATDP1ALDH1A1EHMT2 | |
| SCHEMBL7766697 | 0.71 | EHMT2 (0.38) | MEN1KMT2AALDH1A1EHMT2 | |
| SCHEMBL7767457 | 0.70 | EHMT2 (0.38) | MEN1KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL7765797 | 0.69 | KMT2A (0.38) | MEN1KMT2AALDH1A1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |