SCHEMBL7761892

SCHEMBL7761892

[c]1nc2c(-c3cccs3)cccc2o1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 1/20 0.38
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 4/20 0.38
TDP1 Q9NUW8 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 1/20 0.38
MAOB P27338 1/20 0.38
ADRB1 P08588 1/20 0.37
LTK P29376 1/20 0.36
CDK5 Q00535 1/20 0.36
MST1R Q04912 1/20 0.36
DYRK1A Q13627 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
RAB9A P51151 4/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
NPC1 O15118 3/20 0.35
LTA4H P09960 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7131658 0.80
SCHEMBL3222732 0.77 ALDH1A1 (0.30) ALDH1A1L3MBTL1MAPK1ATMHSD17B10
SCHEMBL5758443 0.77 MAOB (0.39) TDO2KDM4EALDH1A1L3MBTL1MEN1
SCHEMBL3215613 0.75 KIT (0.35)
SCHEMBL2871950 0.75 PDPK1 (0.39) RAB9AADORA2AADORA1
SCHEMBL28546050 0.72 TDO2 (0.42) TDO2KDM4EALDH1A1TDP1L3MBTL1
SCHEMBL11196357 0.71 KDM4E (0.30) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL3287916 0.70 TOP2A (0.41) KDM4EALDH1A1TDP1MEN1MAPT
SCHEMBL558381 0.70 KDM4E (0.36) KDM4EALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL2813661 0.69 ENPP1 (0.38) KDM4EALDH1A1L3MBTL1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001092420-A2 PERYLENE DYES WITH PERSISTENT FLUORESCENCE CAUSED BY STERIC INHIBITION OF AGGREGATION RADIANT COLOR N.V. (BE) 2001-12-06 WO disclosed