Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222732 | 0.87 | ALDH1A1 (0.30) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL7131658 | 0.87 | — | — | |
| SCHEMBL284929 | 0.83 | ACHE (0.40) | TOP2AHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL558381 | 0.79 | KDM4E (0.36) | SMN1; SMN2HPGDALDH1A1IDO1MGAM | |
| SCHEMBL10706324 | 0.79 | NPC1 (0.39) | SMN1; SMN2HPGDALDH1A1HSD17B10CASP3 | |
| SCHEMBL3215613 | 0.78 | KIT (0.35) | — | |
| SCHEMBL6051921 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2HPGDALDH1A1HSD17B10ESR1 | |
| SCHEMBL11158931 | 0.76 | ESR1 (0.46) | SMN1; SMN2ESR1ESR2TP53LMNA | |
| SCHEMBL3230996 | 0.75 | DYRK1A (0.33) | — | |
| SCHEMBL11196357 | 0.74 | KDM4E (0.30) | HPGDALDH1A1HSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838682-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 2007-10-03 | — | — | EP | claimed |
| WO-2006069811-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2006-07-06 | — | — | WO | claimed |
| US-7713452-B2 | Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-05-11 | — | — | US | disclosed |
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) | 2008-03-13 | — | — | US | disclosed |
| EP-1838682-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006069811-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | CRYAB, CRYAA, CRYZ | TOP2A 1361/4885SMN1; SMN2 4736/4885HPGD 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.