Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761892 | 0.77 | TDO2 (0.38) | MAOBALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7112234 | 0.76 | CLK4 (0.33) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL18133657 | 0.75 | ERN1 (0.50) | MAOBALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7214449 | 0.71 | ERN1 (0.46) | MAOBALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL27601843 | 0.68 | ERN1 (0.55) | ALDH1A1KDM4ESMN1; SMN2HSD17B10GAA | |
| SCHEMBL7105969 | 0.68 | NPC1 (0.40) | ALDH1A1KDM4ESMN1; SMN2HSD17B10GAA | |
| SCHEMBL28672054 | 0.65 | SMN1; SMN2 (0.49) | ALDH1A1KDM4ESMN1; SMN2HSD17B10GAA | |
| SCHEMBL8864220 | 0.64 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2HSD17B10GAA | |
| SCHEMBL940312 | 0.63 | NQO2 (0.42) | ALDH1A1KDM4ESMN1; SMN2HSD17B10HPGD | |
| SCHEMBL6067986 | 0.63 | ERN1 (0.52) | ALDH1A1KDM4ESMN1; SMN2HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104403-B1 | HYDROXY PIPECOLATE HYDROXAMIC ACID DERIVATIVES AS MMP INHIBITORS | PFIZER PROD INC (US) | 2006-05-10 | — | — | EP | disclosed |
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MCCLURE KIM F (US) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MMP1, MMP10, MMP3 | MAOB 4492/4885ALDH1A1 2265/4885KDM4E 3877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.