Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761957 | 0.93 | LIPA (0.31) | — | |
| SCHEMBL10127453 | 0.75 | KEAP1 (0.36) | — | |
| SCHEMBL31119442 | 0.72 | — | — | |
| SCHEMBL29518506 | 0.71 | EPHX1 (0.38) | ALOX5 | |
| SCHEMBL1787819 | 0.71 | EPHX1 (0.38) | ALOX5 | |
| SCHEMBL7761975 | 0.70 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL30277414 | 0.68 | EPHX1 (0.33) | ALOX5 | |
| SCHEMBL7761147 | 0.67 | LMNA (0.32) | — | |
| SCHEMBL27960380 | 0.67 | EPHX1 (0.37) | ALOX5 | |
| Carbamic Acid SCHEMBL2342783 | 0.67 | ACHE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1306503-A | 2-fluoro-2-alkyl alkanoamides with anticonvulsant activity | HEINZ NAU (DE) | 2001-08-01 | — | — | CN | disclosed |
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |