Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114636 | 0.96 | SMN1; SMN2 (0.69) | SMN1; SMN2MEN1KMT2AHPGDRECQL | |
| SCHEMBL7119485 | 0.85 | LMNA (0.54) | SMN1; SMN2KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7119082 | 0.84 | RAB9A (0.59) | SMN1; SMN2MEN1KMT2AHPGDKDM4E | |
| SCHEMBL7761958 | 0.81 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AHPGDKDM4E | |
| SCHEMBL7120573 | 0.80 | TP53 (0.55) | SMN1; SMN2HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL7113128 | 0.78 | TAS1R3 (0.64) | SMN1; SMN2MEN1KMT2AHPGDKDM4E | |
| SCHEMBL10943491 | 0.78 | HPGD (0.78) | SMN1; SMN2MEN1KMT2AHPGDRECQL | |
| SCHEMBL12173052 | 0.77 | KMT2A (0.67) | SMN1; SMN2MEN1KMT2AHPGDRECQL | |
| SCHEMBL10988558 | 0.77 | ESR1 (0.74) | SMN1; SMN2HPGDRECQLESR1ALDH1A1 | |
| SCHEMBL7762753 | 0.76 | TRPV1 (0.62) | SMN1; SMN2MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001082924-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |