Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030163 | 0.89 | FOLH1 (0.47) | FOLH1SIRT2HTTTPSAB1TPSD1 | |
| SCHEMBL2030161 | 0.89 | FOLH1 (0.47) | FOLH1SIRT2HTTTPSAB1TPSD1 | |
| SCHEMBL29266083 | 0.85 | FOLH1 (0.46) | FOLH1SIRT2HTTTPSAB1TPSD1 | |
| SCHEMBL5981757 | 0.84 | TPSAB1 (0.55) | FOLH1SIRT2HTTTPSAB1TPSD1 | |
| SCHEMBL2007479 | 0.83 | PPIA (0.43) | HTTMEN1ALDH1A1KMT2A | |
| SCHEMBL30350537 | 0.83 | FOLH1 (0.56) | FOLH1SIRT2HTTTPSAB1TPSD1 | |
| SCHEMBL27892485 | 0.82 | NPY4R (0.42) | FOLH1SIRT2HTTSLC1A3SLC1A1 | |
| SCHEMBL3623326 | 0.81 | FOLH1 (0.51) | FOLH1SIRT2HTTSLC1A3SLC1A1 | |
| SCHEMBL7353231 | 0.81 | HTT (0.41) | FOLH1SIRT2HTTSLC1A3SLC1A1 | |
| SCHEMBL7130463 | 0.78 | LTA4H (0.39) | SLC1A3SLC1A1ALDH1A1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |