Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030161 | 1.00 | FOLH1 (0.47) | FOLH1TPSAB1TPSD1TPSG1SLC1A3 | |
| SCHEMBL29266083 | 0.95 | FOLH1 (0.46) | FOLH1TPSAB1TPSD1TPSG1SLC1A3 | |
| SCHEMBL5981757 | 0.92 | TPSAB1 (0.55) | FOLH1TPSAB1TPSD1TPSG1SLC1A3 | |
| SCHEMBL3623326 | 0.90 | FOLH1 (0.51) | FOLH1SLC1A3SLC1A1HTTCCR6 | |
| SCHEMBL7762891 | 0.89 | FOLH1 (0.42) | FOLH1TPSAB1TPSD1TPSG1SLC1A3 | |
| SCHEMBL30350537 | 0.89 | FOLH1 (0.56) | FOLH1TPSAB1TPSD1TPSG1SLC1A3 | |
| SCHEMBL29517152 | 0.87 | FOLH1 (0.42) | FOLH1TPSAB1TPSD1TPSG1SLC1A3 | |
| SCHEMBL7767627 | 0.85 | FOLH1 (0.43) | FOLH1TPSAB1TPSD1TPSG1SLC1A3 | |
| SCHEMBL7353231 | 0.84 | HTT (0.41) | FOLH1SLC1A3SLC1A1HTTCCR6 | |
| SCHEMBL27892485 | 0.83 | NPY4R (0.42) | FOLH1SLC1A3SLC1A1HTTSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662785-B2 | Selective high affinity polydentate ligands and methods of making such | THE REGENTS OF CALIFORNIA (US) | 2010-02-16 | — | — | US | claimed |
| EP-1088020-B1 | FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF | USTAV MAKROMOLEKULARNI CHEMIE (CZ) | 2002-12-18 | — | — | EP | claimed |
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | claimed |
| US-11471868-B2 | Redox dehydration coupling catalysts and methods related thereto | EMORY UNIVERSITY (US) | 2022-10-18 | — | — | US | disclosed |
| US-20210106677-A1 | VACCINE DEVELOPMENT METHODOLOGY BASED ON AN ADHESION MOLECULE | MATSFIDE, INC. (US) | 2021-04-15 | — | — | US | disclosed |
| US-10874678-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-10646502-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190262364-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2019-08-29 | — | — | US | disclosed |
| US-10292992-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2019-05-21 | — | — | US | disclosed |
| US-10202337-B2 | Method for producing tri-carbobenzoxy-arginine | KANEKA CORPORATION (JP) | 2019-02-12 | — | — | US | disclosed |
| US-9884070-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2018-02-06 | — | — | US | disclosed |
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | disclosed |
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1088020-A1 | FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF | USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) | 2001-04-04 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999064495-A1 | FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF | ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) | 1999-12-16 | — | — | WO | disclosed |
| EP-0118280-B1 | ENZYME INHIBITION | Aktiebolaget Hässle (SE) | 1989-07-12 | — | — | EP | disclosed |
| US-4720484-A | Peptide compounds having a nitrogenous polycyclic structure | ADIR S.A.R.L. (FR) | 1988-01-19 | — | — | US | disclosed |
| EP-0190058-B1 | PEPTIDE DERIVATIVES WITH A POLYCYCLIC NITROGEN STRUCTURE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR (FR) | 1987-12-23 | — | — | EP | disclosed |
| EP-0190058-A1 | Peptide derivatives with a polycyclic nitrogen structure, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1986-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202337-B2 | Method for producing tri-carbobenzoxy-arginine | ARG1, ARGLU1, PRMT1 | FOLH1 2725/4885TPSAB1 1017/4885TPSD1 1988/4885 |
| US-10646502-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | FOLH1 952/4885TPSAB1 4368/4885TPSD1 4532/4885 |
| US-20190262364-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | FOLH1 952/4885TPSAB1 4368/4885TPSD1 4532/4885 |
| US-10874678-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | FOLH1 952/4885TPSAB1 4368/4885TPSD1 4532/4885 |
| US-10292992-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | FOLH1 952/4885TPSAB1 4368/4885TPSD1 4532/4885 |
| US-11471868-B2 | Redox dehydration coupling catalysts and methods related thereto | SCLY, TST, SQOR | FOLH1 2881/4885TPSAB1 3594/4885TPSD1 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.