Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 5/20 | 0.50 |
| ▸ | METAP1 | P53582 | 3/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 2/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766540 | 1.00 | METAP2 (0.50) | METAP2METAP1SLC15A1PPIDCTSC | |
| SCHEMBL7765918 | 0.86 | METAP2 (0.39) | METAP2METAP1SLC15A1CTSCMARS1 | |
| SCHEMBL7766597 | 0.86 | METAP2 (0.39) | METAP2METAP1SLC15A1CTSCMARS1 | |
| SCHEMBL17746783 | 0.84 | SLC15A1 (0.48) | METAP2METAP1SLC15A1CTSCRNPEP | |
| SCHEMBL28969901 | 0.81 | METAP2 (0.48) | METAP2METAP1PPIDCTSCMARS1 | |
| SCHEMBL113612 | 0.80 | METAP2 (0.53) | METAP2METAP1PPIDMARS1RNPEP | |
| SCHEMBL5443843 | 0.80 | METAP2 (0.53) | METAP2METAP1PPIDMARS1RNPEP | |
| SCHEMBL113611 | 0.80 | METAP2 (0.53) | METAP2METAP1PPIDMARS1RNPEP | |
| SCHEMBL26092196 | 0.80 | SLC15A1 (0.42) | METAP2METAP1SLC15A1CTSCRNPEP | |
| SCHEMBL11032201 | 0.79 | ALDH1A1 (0.41) | METAP2METAP1SLC15A1CTSCRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759066-B1 | PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF | DEGUSSA (DE) | 2001-06-27 | — | — | EP | disclosed |
| EP-0759066-A1 | PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF | Degussa Aktiengesellschaft (DE) | 1997-02-26 | — | — | EP | disclosed |
| WO-1995030740-A1 | PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1995-11-16 | — | — | WO | disclosed |