Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265107 | 0.83 | TLR8 (0.49) | NQO2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29120679 | 0.82 | ALOX5 (0.50) | NQO2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29120678 | 0.82 | ALOX5 (0.50) | NQO2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29120680 | 0.81 | NQO2 (0.48) | NQO2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL21585548 | 0.80 | NQO2 (0.55) | NQO2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7655964 | 0.80 | CYP1A2 (0.47) | MAPTMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL7652962 | 0.79 | CYP1A2 (0.46) | MAPTTDP1CYP1A2CYP3A4 | |
| SCHEMBL7655581 | 0.79 | HTR6 (0.37) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7649355 | 0.78 | CHRNA7 (0.37) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL10436098 | 0.77 | NQO2 (0.52) | NQO2KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001091796-A2 | METHODS, COMPOUNDS AND COMPOSITIONS FOR TREATING GOUT | GUILFORD PHARMACEUTICALS INC. (US) | 2001-12-06 | — | — | WO | disclosed |