SCHEMBL7763133

SCHEMBL7763133

C=Cc1cccc2cccc(Cl)c12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
CYP1A2 P05177 3/20 0.38
CYP2A6 P11509 2/20 0.38
MEN1 O00255 8/20 0.38
KMT2A Q03164 8/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
GAA P10253 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CYP1A1 P04798 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
CYP1B1 Q16678 1/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 1/20 0.36
NPC1 O15118 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278142 0.84 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2A6KMT2ATSHR
SCHEMBL29434209 0.84 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2A6KMT2ATSHR
SCHEMBL8446224 0.81 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP2A6KMT2ATSHR
SCHEMBL29587339 0.78 MEN1 (0.48) ALDH1A1CYP1A2CYP2A6MEN1KMT2A
SCHEMBL5276864 0.78 MEN1 (0.48) ALDH1A1CYP1A2CYP2A6MEN1KMT2A
SCHEMBL19601465 0.78 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP2A6KMT2AGAA
SCHEMBL29620230 0.75 TSHR (0.53) ALDH1A1CYP1A2CYP2A6MEN1KMT2A
SCHEMBL29620231 0.75 TSHR (0.53) ALDH1A1CYP1A2CYP2A6MEN1KMT2A
SCHEMBL4103602 0.75 TSHR (0.53) ALDH1A1CYP1A2CYP2A6MEN1KMT2A
SCHEMBL40188 0.75 ALDH1A1 (0.65) ALDH1A1CYP1A2CYP2A6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007147775-A1 PROCESS FOR SYNTHESIS OF AROMATIC COMPOUNDS DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 2007-12-27 WO disclosed
WO-2001092276-A1 PREPARATION OF PHOSPHINOARYLALKENES AND POLYMERS THEREOF CYTEC TECHNOLOGY CORP. (US) 2001-12-06 WO disclosed