Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17822177 | 0.88 | LMNA (0.50) | KMT2ALMNARAB9ARIPK1CYP1A2 | |
| SCHEMBL2850028 | 0.81 | RIPK1 (0.49) | KMT2AMAPTLMNARAB9ARIPK1 | |
| SCHEMBL21538589 | 0.79 | RIPK1 (0.47) | KMT2AMAPTLMNARAB9ARIPK1 | |
| SCHEMBL17161705 | 0.77 | RIPK1 (0.53) | KMT2AMAPTLMNARAB9ARIPK1 | |
| SCHEMBL4783910 | 0.76 | SMN1; SMN2 (0.41) | MAPTLMNARAB9ARIPK1CYP3A4 | |
| SCHEMBL15955100 | 0.75 | MAPT (0.57) | KMT2AMAPTCYP1A2CYP3A4RECQL | |
| SCHEMBL27897911 | 0.75 | MAPT (0.57) | KMT2AMAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL27339130 | 0.75 | KMT2A (0.41) | KMT2AMAPTLMNARAB9ARIPK1 | |
| SCHEMBL10703980 | 0.74 | RAB9A (0.50) | KMT2AMAPTLMNARAB9ARIPK1 | |
| SCHEMBL8938136 | 0.74 | SMN1; SMN2 (0.43) | KMT2AMAPTLMNARAB9ARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102744-A1 | NOVEL METHOD FOR PREPARING OPTICALLY ACTIVE ALPHA-AMINONITRILES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000075104-A1 | NOVEL METHOD FOR PREPARING OPTICALLY ACTIVE ALPHA-AMINONITRILES | AVENTIS CROPSCIENCE SA (FR) | 2000-12-14 | — | — | WO | disclosed |