SCHEMBL7763277

SCHEMBL7763277

CNS(=O)(=O)c1ccc(C(=O)O)c(C)c1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
MAPT P10636 1/20 0.39
ALDH1A1 P00352 5/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 3/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
LMNA P02545 1/20 0.38
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
CRHBP P24387 1/20 0.36
KMT2A Q03164 1/20 0.36
CRHR2 Q13324 1/20 0.36
APP P05067 1/20 0.36
CA12 O43570 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27316603 0.81 ALDH1A1 (0.40) CYP1A2ALDH1A1HSD17B10HPGDCA1
SCHEMBL27412126 0.75 NPSR1 (0.44) ALDH1A1HPGDMMP1MMP2MMP9
SCHEMBL8548517 0.75 ALDH1A1 (0.49) MAPTALDH1A1HSD17B10HPGDCA1
SCHEMBL8552433 0.75 METAP2 (0.51) CYP1A2MAPTALDH1A1HSD17B10HPGD
SCHEMBL28140600 0.74 CA12 (0.37) CYP1A2MAPTALDH1A1HSD17B10HPGD
SCHEMBL6334298 0.73 CYP1A2 (0.48) CYP1A2ALDH1A1HSD17B10HPGDKDM4E
SCHEMBL27263387 0.72 ALDH1A1 (0.36) CYP1A2ALDH1A1HSD17B10HPGDCA2
SCHEMBL10334261 0.72 CYP1A2 (0.38) CYP1A2ALDH1A1HSD17B10HPGDCA1
SCHEMBL4433906 0.72 CA1 (0.70) CYP1A2MAPTALDH1A1HSD17B10HPGD
SCHEMBL27360371 0.72 KDM4C (0.44) CYP1A2MAPTALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0945449-B1 Process for the preparation of saccharincarboxylic acid halides BASF AG (DE) 2001-05-23 EP disclosed
US-5981758-A Preparation of saccharincarbonyl halides BASF AKTIENGESELLSCHAFT (DE) 1999-11-09 US disclosed
EP-0945449-A1 Process for the preparation of saccharincarboxylic acid halides BASF AKTIENGESELLSCHAFT (DE) 1999-09-29 EP disclosed