Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.58 |
| ▸ | RAB9A | P51151 | 13/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763484 | 0.86 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL7120067 | 0.83 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL7118156 | 0.83 | TAS1R3 (0.61) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL7113169 | 0.81 | SNCA (0.54) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7121710 | 0.80 | HPGD (0.56) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL12521437 | 0.77 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL7124123 | 0.77 | ALDH1A1 (0.64) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL2917029 | 0.76 | NPC1 (0.82) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL28937078 | 0.76 | TOP1 (0.74) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL11303092 | 0.76 | CYP3A4 (0.60) | NPC1RAB9ASMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A3, SLC34A1 | NPC1 1199/4885RAB9A 2291/4885SMN1; SMN2 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.