Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 7/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15758444 | 0.84 | FAAH (0.54) | FAAHCES1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL28610213 | 0.82 | FAAH (0.65) | FAAHCES1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL872525 | 0.82 | FAAH (0.39) | FAAHCES1CYP1A2KMT2AMEN1 | |
| SCHEMBL29286403 | 0.81 | FAAH (0.50) | FAAHCES1SOAT1CYP1A2CYP2C19 | |
| Oleamide SCHEMBL28407228 | 0.80 | FAAH (0.74) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL28516851 | 0.80 | FAAH (0.51) | FAAHCES1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL27500926 | 0.79 | CNR2 (0.48) | FAAHCES1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL6142280 | 0.78 | FAAH (0.44) | FAAHCES1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL109910 | 0.77 | FAAH (0.51) | FAAHCES1SOAT1CYP1A2CYP2C19 | |
| SCHEMBL28508425 | 0.77 | FAAH (0.49) | FAAHSOAT1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102836-A1 | WATER-IN-OIL MICROEMULSION FOR PROVIDING COSMETIC ATTRIBUTES TO FABRIC SOFTENING BASE COMPOSITION | Colgate-Palmolive Company (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006690-A1 | WATER-IN-OIL MICROEMULSION FOR PROVIDING COSMETIC ATTRIBUTES TO FABRIC SOFTENING BASE COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |