Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.39 |
| ▸ | CES1 | P23141 | 10/20 | 0.39 |
| ▸ | CES2 | O00748 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874815 | 0.88 | FAAH (0.48) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL7764261 | 0.82 | FAAH (0.49) | FAAHCES1MEN1CYP1A2KMT2A | |
| SCHEMBL28363537 | 0.79 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL7570977 | 0.76 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL2780739 | 0.76 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| Octadecanoic Acid Amide SCHEMBL1411989 | 0.76 | SOAT1 (0.47) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9157001 | 0.76 | SMPD1 (0.40) | MEN1KMT2AHSD17B10CA12CA2 | |
| SCHEMBL28646473 | 0.75 | FAAH (0.42) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL19409848 | 0.75 | FAAH (0.42) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL11055861 | 0.75 | DGKA (0.50) | MEN1KMT2ACA12CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2618801-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE HYGROSCOPIC SALT, AT LEAST ONE AROMATIC POLYOL ETHER AND AT LEAST ONE DIOL, AND COSMETIC TREATMENT PROCESS | L'Oréal (FR) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038536-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE HYGROSCOPIC SALT, AT LEAST ONE AROMATIC POLYOL ETHER AND AT LEAST ONE DIOL, AND COSMETIC TREATMENT PROCESS | L'OREAL (FR) | 2012-03-29 | — | — | WO | disclosed |