Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142283 | 0.81 | FAAH (0.43) | FAAHCES1EPHX2CNR2TRPV1 | |
| SCHEMBL27318374 | 0.81 | FAAH (0.43) | FAAHCES1EPHX2CNR2TRPV1 | |
| SCHEMBL109910 | 0.80 | FAAH (0.51) | FAAHCES1SOAT1MEN1TP53 | |
| SCHEMBL26105777 | 0.80 | MGLL (0.53) | EPHX2CNR2TRPV1CNR1 | |
| SCHEMBL15758444 | 0.80 | FAAH (0.54) | FAAHCES1SOAT1MEN1TP53 | |
| SCHEMBL28405188 | 0.79 | CNR1 (0.45) | EPHX2CNR2TRPV1CNR1CYP1A2 | |
| SCHEMBL7764261 | 0.78 | FAAH (0.49) | FAAHCES1SOAT1MEN1TP53 | |
| SCHEMBL26107461 | 0.77 | MGLL (0.59) | FAAHEPHX2CNR2TRPV1CNR1 | |
| SCHEMBL27500926 | 0.76 | CNR2 (0.48) | FAAHCES1EPHX2CNR2TRPV1 | |
| SCHEMBL29286403 | 0.76 | FAAH (0.50) | FAAHCES1SOAT1MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244475-B1 | METHOD OF MAKING TRIDIMENSIONALLY SHAPED ABSORBENT FOAM | PROCTER & GAMBLE (US) | 2005-01-12 | — | — | EP | disclosed |
| EP-0888137-B1 | HETEROGENEOUS FOAM MATERIALS | PROCTER & GAMBLE (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-1222213-A1 | APPARATUS AND PROCESS FOR IN-LINE PREPARATION OF HIPEs | THE PROCTER & GAMBLE COMPANY (US) | 2002-07-17 | — | — | EP | disclosed |
| US-6406648-B1 | MOLDINGS, FOAM, SHAPING, WATER PHASE AND OIL PHASE, HIGH INTERNAL PHASE EMULSION | THE PROCTER & GAMBLE COMPANY | 2002-06-18 | — | — | US | disclosed |
| US-6369121-B1 | HIGH INTERNAL PHASE EMULSION (HIPE) USING A SINGLE PASS THROUGH THE STATIC MIXER | THE PROCTER & GAMBLE COMPANY | 2002-04-09 | — | — | US | disclosed |
| EP-0802929-B1 | ABSORBENT FOAM MATERIALS FOR AQUEOUS FLUIDS MADE FROM HIGH INTERNAL PHASE EMULSIONS HAVING VERY HIGH WATER-TO-OIL RATIOS | PROCTER & GAMBLE (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2001027165-A1 | APPARATUS AND PROCESS FOR IN-LINE PREPARATION OF HIPEs | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |
| US-5869171-A | OPEN-CELLED ABSORBENT ARTICLE COMPRISING A TOPSHEET, POLYMERIC CORE AND BACKSHEET | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0888137-A1 | HETEROGENEOUS FOAM MATERIALS | THE PROCTER & GAMBLE COMPANY (US) | 1999-01-07 | — | — | EP | disclosed |
| US-5856366-A | OPEN CELL FOAM FROM WATER IN OIL EMULSION | THE PROCTER & GAMBLE COMPANY (US) | 1999-01-05 | — | — | US | disclosed |
| US-5817704-A | INTERCONNECTING OPENED-CELL FOAMS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0802823-B1 | RECIRCULATING A PORTION OF HIGH INTERNAL PHASE EMULSIONS PREPARED IN A CONTINUOUS PROCESS | PROCTER & GAMBLE (US) | 1998-09-30 | — | — | EP | disclosed |
| US-5744506-A | FLEXIBILITY, MICROPOROUS OPEN CELLED FOAM | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-28 | — | — | US | disclosed |
| US-5741581-A | Absorbent foam materials for aqueous fluids made from high internal phase emulsions having very high water-to-oil ratios | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0802823-A1 | RECIRCULATING A PORTION OF HIGH INTERNAL PHASE EMULSIONS PREPARED IN A CONTINUOUS PROCESS | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-29 | — | — | EP | disclosed |
| EP-0802929-A1 | ABSORBENT FOAM MATERIALS FOR AQUEOUS FLUIDS MADE FROM HIGH INTERNAL PHASE EMULSIONS HAVING VERY HIGH WATER-TO-OIL RATIOS | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1997032612-A1 | HETEROGENEOUS FOAM MATERIALS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-12 | — | — | WO | disclosed |
| US-5650222-A | DIAPERS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-22 | — | — | US | disclosed |
| WO-1996021680-A1 | ABSORBENT FOAM MATERIALS FOR AQUEOUS FLUIDS MADE FROM HIGH INTERNAL PHASE EMULSIONS HAVING VERY HIGH WATER-TO-OIL RATIOS | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-18 | — | — | WO | disclosed |
| WO-1996021505-A1 | RECIRCULATING A PORTION OF HIGH INTERNAL PHASE EMULSIONS PREPARED IN A CONTINUOUS PROCESS | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-18 | — | — | WO | disclosed |