Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760522 | 0.81 | SIRT6 (0.54) | AKR1C3ALDH1A1MAPT | |
| SCHEMBL7763392 | 0.76 | MAPT (0.52) | KDM4EALDH1A1MAPTCCR1 | |
| SCHEMBL5776667 | 0.73 | GPR119 (0.51) | AKR1C3SLC6A9GPR119CTSBCTSS | |
| SCHEMBL7768602 | 0.72 | AKR1C3 (0.55) | AKR1C3SLC6A9GPR119CTSBCTSS | |
| SCHEMBL22495385 | 0.72 | MAPT (0.58) | AKR1C3RAD52KDM4EGPR119ALDH1A1 | |
| SCHEMBL27643066 | 0.71 | AKR1C3 (0.68) | AKR1C3SLC6A9GPR119CTSBCTSS | |
| SCHEMBL3486778 | 0.71 | GPR119 (0.61) | AKR1C3KDM4EGPR119CTSBCTSS | |
| SCHEMBL7768608 | 0.70 | MAPT (0.60) | ALDH1A1MAPTCYP3A4 | |
| SCHEMBL28170767 | 0.70 | AKR1C3 (0.58) | AKR1C3KDM4EGPR119ALDH1A1MAPT | |
| SCHEMBL12826096 | 0.69 | LMNA (0.59) | AKR1C3GPR119ALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561520-B1 | Toner compositions with coupled liquid glass resins and image developing method using them | XEROX CORP (US) | 2001-06-13 | — | — | EP | claimed |
| EP-1104413-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOUNDS CONTAINING THEM | ELI LILLY AND COMPANY LIMITED (GB) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000008006-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOUNDS CONTAINING THEM | ELI LILLY AND COMPANY LIMITED (GB) | 2000-02-17 | — | — | WO | disclosed |