Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 4/20 | 0.61 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.56 |
| ▸ | NT5E | P21589 | 4/20 | 0.52 |
| ▸ | MGMT | P16455 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | AHCY | P23526 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21145007 | 0.86 | SLC29A1 (0.74) | SLC29A1ADORA2AADORA2BMGMTADORA3 | |
| SCHEMBL8530562 | 0.86 | HINT1 (0.62) | HINT1SLC29A1ADORA2AADORA2BNT5E | |
| SCHEMBL22193718 | 0.80 | SLC29A1 (0.63) | SLC29A1ADORA2AADORA2BMGMTADORA3 | |
| SCHEMBL8971138 | 0.79 | SLC29A1 (0.62) | SLC29A1ADORA2AADORA2BNT5EMGMT | |
| SCHEMBL8971129 | 0.79 | SLC29A1 (0.62) | SLC29A1ADORA2AADORA2BNT5EMGMT | |
| SCHEMBL8531895 | 0.78 | ALDH1A1 (0.57) | HINT1SLC29A1ADORA2AADORA2BNT5E | |
| SCHEMBL8532634 | 0.78 | ALDH1A1 (0.57) | HINT1ADORA2AADORA2BNT5EADORA3 | |
| SCHEMBL27621467 | 0.78 | SLC29A1 (0.66) | SLC29A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL8529529 | 0.78 | HINT1 (0.63) | HINT1SLC29A1ADORA2AADORA2BNT5E | |
| SCHEMBL8529428 | 0.78 | HINT1 (0.61) | HINT1SLC29A1ADORA2AADORA2BNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085221-A2 | ASSESSING LEVELS OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE IN VIVO | DUKE UNIVERSITY (US) | 2001-11-15 | — | — | WO | disclosed |