Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772518 | 0.89 | LMNA (0.43) | KMT2ALMNAKIF11MAPTMEN1 | |
| SCHEMBL7770269 | 0.88 | LMNA (0.40) | CASRKMT2ALMNAKIF11MAPT | |
| SCHEMBL7772500 | 0.86 | LMNA (0.40) | KMT2ALMNAKIF11L3MBTL1KDM4E | |
| SCHEMBL7764611 | 0.84 | LMNA (0.39) | LMNAKIF11 | |
| SCHEMBL7764613 | 0.84 | LMNA (0.39) | LMNAKIF11 | |
| SCHEMBL7772524 | 0.80 | KIF11 (0.48) | CASRKMT2ALMNAKIF11MAPT | |
| Hydrochloric Acid SCHEMBL7769555 | 0.79 | MLYCD (0.41) | KMT2AMAPTMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL7768603 | 0.79 | RAB9A (0.48) | LMNAMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL8607099 | 0.76 | CASR (0.47) | CASRKMT2ALMNAMAPK1L3MBTL1 | |
| SCHEMBL6319503 | 0.75 | KMT2A (0.63) | CASRKMT2AMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |