Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805221 | 0.84 | ADK (0.51) | ADKCA1CA2GSK3BTSHR | |
| SCHEMBL9805553 | 0.80 | ADK (0.65) | ADK | |
| SCHEMBL9805237 | 0.80 | ADK (0.65) | ADK | |
| SCHEMBL9346495 | 0.78 | ADK (0.39) | ADKCA1CA2CA12CA9 | |
| Adenine SCHEMBL14636444 | 0.78 | HIF1A (0.49) | ADK | |
| SCHEMBL9805157 | 0.78 | ADK (0.57) | ADKCA1CA2TSHR | |
| SCHEMBL11652071 | 0.78 | PAX8 (0.37) | ADKCA1CA2 | |
| SCHEMBL11652097 | 0.78 | PAX8 (0.37) | ADKCA1CA2 | |
| Ribose (Furanose) SCHEMBL2505730 | 0.77 | ADK (0.40) | ADKTSHR | |
| Ribose (Furanose) SCHEMBL4542668 | 0.77 | ADK (0.40) | ADKTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085221-A2 | ASSESSING LEVELS OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE IN VIVO | DUKE UNIVERSITY (US) | 2001-11-15 | — | — | WO | disclosed |