Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652097 | 1.00 | PAX8 (0.37) | PAX8ADKADORA3CA1CA2 | |
| SCHEMBL31529230 | 0.83 | PAX8 (0.52) | PAX8SMN1; SMN2 | |
| SCHEMBL7764674 | 0.78 | ADK (0.54) | ADKCA1CA2 | |
| SCHEMBL31529191 | 0.77 | IRAK4 (0.47) | PAX8ADKCA1CA2 | |
| SCHEMBL11649574 | 0.72 | PAX8 (0.65) | PAX8 | |
| SCHEMBL11651719 | 0.72 | PAX8 (0.65) | PAX8 | |
| SCHEMBL17612653 | 0.67 | ADK (0.44) | ADKCA1CA2SMN1; SMN2 | |
| SCHEMBL31529113 | 0.67 | CYP3A4 (0.45) | PAX8ADKADORA3 | |
| SCHEMBL797545 | 0.66 | LMNA (0.51) | — | |
| SCHEMBL30473749 | 0.66 | LMNA (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086416-A | ANTITUMOR | STANFORD RESEARCH INSTITUTE (US) | 1978-04-25 | — | — | US | disclosed |