Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.38 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346477 | 0.81 | EGLN1 (0.34) | CA12CA1CA2CA9 | |
| SCHEMBL9346485 | 0.79 | ADK (0.42) | ADKCA12CA1CA2CA9 | |
| SCHEMBL7764674 | 0.78 | ADK (0.54) | ADKCA12CA1CA2CA9 | |
| SCHEMBL9346512 | 0.74 | ADK (0.40) | ADKCA12CA1CA2CA9 | |
| Adenine SCHEMBL14636444 | 0.74 | HIF1A (0.49) | ADKHSPA5HSPA8RXFP1SLC29A1 | |
| Ribose (Furanose) SCHEMBL4542668 | 0.73 | ADK (0.40) | ADKHSPA5HSPA8RXFP1SLC29A1 | |
| Ribose (Furanose) SCHEMBL2505730 | 0.73 | ADK (0.40) | ADKHSPA5HSPA8RXFP1SLC29A1 | |
| Adenine SCHEMBL9007542 | 0.69 | FBP1 (0.46) | ADKHSPA5HSPA8RXFP1SLC29A1 | |
| SCHEMBL9346479 | 0.68 | HIF1A (0.38) | HSPA5HSPA8RXFP1SLC29A1HIF1A | |
| SCHEMBL9805221 | 0.68 | ADK (0.51) | ADKRXFP1CA1CA2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353268-B1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INST (US) | 1994-08-10 | — | — | EP | claimed |
| EP-0353268-B1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INST (US) | 1994-08-10 | — | — | EP | disclosed |